Sproutcore
JavaScript Application Framework - JS library only
Durandal
A cross-device, cross-platform client framework written in JavaScript and designed to make building Single Page Applications (SPAs) easy to create and maintain.
Ink
An HTML5/CSS3 framework used at SAPO for fast and efficient website design and prototyping
Head js
The only script in your HEAD. Head JS loads JavaScript files in parallel like images without blocking the page. Your page will be faster. Even with a single combined file.
Steal
Gets JavaScript
Fast.js
Faster user-land reimplementations for several common builtin native JavaScript functions.
Script.js
Asyncronous JavaScript loader and dependency manager
Datacamp Light
Convert any blog or website to an interactive learning platform for data science
Bootstrap.native
If you are looking for Bootstrap without jQuery or vanilla Javascript for Bootstrap, this is the place to get started.
Rambda
Faster alternative to Ramda in just 10kB
Jsblocks
Better MV-ish Framework
Qooxdoo
A Universal JavaScript Framework
Pencilblue
Full stack online publishing and CMS for Node.js
Batman
Fighting Crime and Kicking Apps
Node Pg Migrate
Node.js database migration management for Postgresql
Libretaxi
LibreTaxi, free and open source Uber/Lyft alternative to connect passengers and drivers.
Overmind
Overmind - Frictionless state management