Bootstrap.native
If you are looking for Bootstrap without jQuery or vanilla Javascript for Bootstrap, this is the place to get started.
Sammy
Sammy is a tiny javascript framework built on top of jQuery, It's RESTful Evented Javascript.
JavascriptMVC
Develop with direction! With CanJS, jQuery++, FuncUnit, Steal, DocumentJS.
Ink
An HTML5/CSS3 framework used at SAPO for fast and efficient website design and prototyping
Black Hole.js
Renders black hole gravitational lensing effects in an image canvas using WebGL, glfx.js, and numeric.js
Nuclear Js
Reactive Flux built with ImmutableJS data structures. Framework agnostic.
Director
a tiny and isomorphic URL router for JavaScript
Dojo
Dojo saves you time and scales with your development process, using web standards as its platform. It’s the toolkit experienced developers turn to for building high quality desktop and mobile web applications.
Inferno
An extremely fast, React-like JavaScript library for building modern user interfaces
Serenade.js
Client side MVC framework
Wee
Blueprint for modern web development
Venus.js
where bugs go to die
Simplecart
A simple javascript shopping cart that easily integrates with your current website.
Aura
A scalable, event-driven JavaScript architecture for developing widget-based applications. Works with Backbone.js and other frameworks.
Tungstenjs
Tungsten.js is a modular framework for creating web UIs with high-performance rendering on both server and client.
Path.js
Simple, lightweight routing for web browsers