Electron
Build cross-platform desktop apps with JavaScript, HTML, and CSS
Mithril.js
A Javascript Framework for Building Brilliant Applications
Sdk Js
Tanker client-side encryption SDK for JavaScript
Ember
Ember.js is a JavaScript framework that does all of the heavy lifting that you'd normally have to do by hand. There are tasks that are common to every web app; Ember.js does those things for you, so you can focus on building killer features and UI.
Meteor
Meteor, an ultra-simple, database-everywhere, data-on-the-wire, pure-Javascript web framework.