Audio5js
The HTML5 Audio Compatibility Layer
Waud
Web Audio Library
Flac.js
FLAC decoder in JavaScript
Howler.js
Javascript audio library for the modern web.
Pizzicato
Library to simplify the way you create and manipulate sounds with the Web Audio API.
Tone.js
A Web Audio framework for making interactive music in the browser.
Sound Manager 2
A JavaScript Sound API supporting MP3, MPEG4 and HTML5 audio + (experimental) RTMP, providing reliable cross-browser/platform audio control in as little as 10 KB. BSD licensed.
Wad
Web Audio DAW. Use the HTML5 Web Audio API for dynamic sound synthesis. It's like jQuery for your ears.
Speak.js
Text-to-Speech in JavaScript using eSpeak
Alpha Tab
alphaTab is a cross platform music notation and guitar tablature rendering library.
Teoria
A JavaScript music theory framework.