Frozen is an open-source HTML5 game engine delivering ease-of-use, rapid development through tooling and modularity.
Blend4Web is a tool for interactive 3D visualization on the Internet
phina.js is game library
Kiwi.js is a blazingly fast mobile & desktop browser based HTML5 game framework. It uses CocoonJS for publishing to the AppStore.
Egret is a brand new open mobile game and application engine which allows you to quickly build mobile games and apps on Android,iOS and Windows.
HTML5 game framework for web and iOS
JSIso - An HTML5 Canvas Tile Engine