Bootstrap.native
If you are looking for Bootstrap without jQuery or vanilla Javascript for Bootstrap, this is the place to get started.
Asm Dom
A minimal WebAssembly virtual DOM to build C++ SPA (Single page applications)
Kute.js
KUTE.js is a native Javascript animation engine featuring badass performance, morphSVG, drawSVG, 2D and 3D transforms, SVG transforms, colors, as well as other CSS3 properties or presentation attributes.
Mobiscroll
The customizable HTML5 spinner/scroller control for touch devices like smartphones and tablets
Reactable
Fast, flexible, and simple data tables in React
Juggling DB
Multi-database ORM: redis, mongodb, mysql, sqlite, postgres, neo4j, memory... Many databases, common API.
Audio.js
A cross-browser javascript wrapper for the html5 audio tag
Engine
GSS engine
Simple Parallax
Simple and tiny JavaScript library to add parallax animations on any images
Qooxdoo
A Universal JavaScript Framework
Batman
Fighting Crime and Kicking Apps
Pencilblue
Full stack online publishing and CMS for Node.js
jQuery Focuspoint
jQuery plugin for 'responsive cropping'. Dynamically crop images to fill available space without cutting out the image's subject. Great for full-screen images.
Egjs Infinitegrid
A module used to arrange card elements including content infinitely on a grid layout.
Glslify
A node.js-style module system for GLSL!
Web Audio Api
The Web Audio API, developed by the W3C Audio WG
Garlic.js
Garlic.js allows you to automatically persist your forms' text and select field values locally, until the form is submitted. This way, your users don't lose any precious data if they accidentally close their tab or browser.